All activities of the International Society of DAO Deficiency have now been absorbed and incorporated into the International Institute of DAO Deficiency.

This integration reinforces our commitment to advancing research, education, and international collaboration in the study of DAO Deficiency and histamine-related disorders.

From now on, all institutional updates, scientific projects, and community initiatives will be shared directly through the DAO Institute’s communication channels.

On November 20 at 18:00 (CET), the DAO Institute will host a new interactive masterclass led by registered dietitian and licensed member Clara Elvers.
An open session where participants can interact live, ask questions, and learn practical guidance on DAO Deficiency and low-histamine diets.
Registration fee: €15 — limited spots available.
Get your ticket here!

We welcome the new members joining the sixth edition of the Licensing Program, representing five new countries. With each edition, our community grows stronger as a global network of professionals committed to improving patients’ quality of life.
👉 Applications for the next edition are now open: Learn more here

On September 27, the DAO Institute took part in a scientific session in Cancún organized by Laboratorios Columbia, attended by over one hundred neurologists and rheumatologists. Director Adriana Duelo MSc RDN presented the global spectrum of DAO Deficiency symptoms and its clinical nutrition approach.

A new study led by the University of Barcelona in collaboration with the DAO Institute has just been published in Journal of Clinical Medicine, titled:

“Improvement of Histamine Intolerance Symptoms in Pregnant Women with Diamine Oxidase Deficiency: An Exploratory Study.”

This research explores how DAO enzyme activity and histamine-related symptoms change throughout pregnancy, offering new insights into the connection between histamine metabolism and maternal health.

👉 Read the full article

The DAO Institute expands its resource library with a new guide on food substitutes for low-histamine diets. Available exclusively to licensed members, this material supports dietary adaptation for patients with DAO Deficiency.

Today, July the 24, Prof. Dr. Marcus Zanetti (Hospital das Clínicas FMUSP, São Paulo) will host an exclusive session for DAO Institue Licensed members. During the webinar, Dr. Zanetti will discuss stress and anxiety from a diagnostic perspective, DAO activity and histaminergic transmission, lifestyle-based interventions, and the impact of histamine intolerance on mental health.

On Tuesday, June 8th, Lic. Ma Pilar de León, member of the International Institute of DAO Deficiency, was interviewed on Medical TV in Salta, Argentina. During the interview, she explained the main symptoms associated with histaminosis due to DAO deficiency, which foods should be avoided on a low-histamine diet, and how to identify if someone might be suffering from DAO Deficiency. A valuable contribution to raising awareness about this still under-recognized condition. You can watch the full interview by clicking here.

The International Institute of DAO Deficiency is launching its 6th call for pre-enrollment for healthcare professionals who wish to specialize in DAO Deficiency and become part of an international professional community. New available locations include the United States, Germany, Belgium, and the Netherlands, among others. Click here to submit your application.

Last Friday, May 16th, the Institute’s licensees received an exclusive webinar led by Dr. Francisco Guarner, Gastroenterologist at Centro Médico Teknon (Barcelona). During the session, Dr. Guarner discussed the current evidence linking the microbiota and inflammatory bowel disease (IBD), a condition commonly seen in patients with DAO deficiency.