DAO enzyme according to its origin: animal or vegetable?

(An article written in August 2022 and updated in May 2024) We know that the Diamine Oxidase (DAO) enzyme is the main responsible for metabolizing a molecule that we ingest through the diet called histamine. This biogenic amine that we find in many foods has not any functions in our body (unlike the one we […]

Omega-3 in low-histamine diets

If you are following a low-histamine diet it is essential to ensure the omega-3 contribution through the food ingestion or supplementation. Once the enzyme deficiency has been diagnosed, through the genetic test or the DAO activity in blood, nutrition treatment begins with a low-histamine and other amines diet which also favor their accumulation. On the […]

Which substances can act as natural antihistamines?

It has been described certain antihistamines which block the Diamine Oxyadase (DAO) enzyme. In this sense, the symptoms of DAO deficiency could be worse after taking this medication and, for this reason, there is great interest in finding natural substances which act as antihistamines and do not inhibit the enzyme. Antihistamines are a class of […]

Key nutrients in a low histamine diet

Once the deficiency of the Diamine Oxidase (DAO) enzyme was diagnosed, we begin the treatment with a low-histamine diet and other amines that also promote its accumulation, such as putrestine or cadaverine. In addition, it will also be vitally important to take into account those foods that release endogenous histamine or blockers of the DAO […]

SIBO, histamine and DAO deficiency

Millions of bacteria and microorganisms coexist in our intestines. These must be in harmony and maintain a homeostasis among them, with a greater proportion of beneficial bacteria and few pathogenic bacteria. In addition to the type of bacteria, the place where these bacteria live is also important, and most of them live in the most […]